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MegaSporeBiotic is the first all-spore, pharmaceutical grade probiotic that survives the gastric environment naturally. It is a foundational nutritional food that provides true probiotic benefits.

MegaSporeBioticTM introduces HU36TM, the first commercially available carotenoid rich probiotic. This strain naturally produces forms of lycopene, astaxanthin, zeaxanthin, beta carotene and lutein in your digestive tract right at the site of absorption. This makes them the most bioavailable antioxidants known to science.

To learn more, read the patient handout here and check out the dosing guidelines here.


Save 20% when you order three or more!

Our coach Ann Melin combines a dose of Megaspore with a dose of saccharomyces boulardii.  I (Bridgit) have been doing one capsule of each twice a day at breakfast and dinner for a great result!  You can find saccharomyces boulardii at our shop under the name GI Assist. For more powerful gut healing, check out our Gut Restoration Kit, which includes Megaspore, saccharomyces boulardii, and GI Restore at a discount.

Supplement Facts

Serving Size: 2 capsules
Servings Per Container: 30
Proprietary Probiotic Blend: 4 billion spore cells
Bacillus Licheniformis
+ Produces proteases needed for protein digestion

 + Produces full spectrum of B vitamins

Suggested Use

The recommended maintenance dose is 2 capsules a day.  These can be taken both at once, or one taken with lunch, and one with dinner.  Once you have stabilized your gut, you could possibly take even less, like take 2 pills 3 times a week.

It's best to take with meals containing protein.  Taking Megaspore with meals can help support digestion.  However you can take all your daily dose at one meal, and it seems to pack more punch for healing.  It's up to you.

However, when you first take it, start with 1 capsule (or 1/2 capsule if you are sensitive) and watch for reactions. Skip a day.  If you have no adverse reactions, then you can move to 2 /day (or 1/day next if you are proceeding slowly).

If you are recovering from antibiotic use, a leaky gut, etc, you may need to take more Megaspore for a while, like 4-6 weeks.

If you're taking antibiotics, take at least 4 hours away from your antibiotic dose.

Die-off symptoms are possible, i.e. bloating and loose stool. This has never happened for me. But if you have an abundance of unhealthy bacteria in your gut, you could get symptoms as these bacteria 'die off.'


Traveling with MegaSporeBioticTM is convenient, uncomplicated, and practical because it does not require refrigeration. MegaSporeBioticTM survives and arrives at the site of colonization alive, so it can perform its probiotic function!


MegaSpore FAQ:

1.  Can kids take Megaspore?

Yes, kids can take Megaspore, at a dose smaller than for adults.  If you have an infant or child under 25 pounds, I would just use a small sprinkle on food or on your finger (for a baby).  You can also mix it into breast milk or formula.  I would use it with a small child primarily to recover from antibiotic usage, or to avoid antibiotic usage.  

Some children, especially if born via C section, may not be developing their gut microbiome properly, and the Megaspore could help. You might see this manifest in irregular bowel patterns or food sensitivities. We have a nice podcast on infant health with Dr. Laura Brayton here.

Please discuss any probiotic therapy with your holistic or functional pediatrician.  If your child is under 50 pounds, I would suggest 1/2 pill.  If your child is over 50 pounds, then 1 pill.  As we learned in the above questions, there could be times that a higher dose is appropriate for an older child.

2.  What if I have SIBO (Small Intestine Bacterial Overgrowth)?

Megaspore is compatible for people with SIBO.  However you will probably need other support to heal your SIBO.  We mentioned a few ideas on the webinar with Kiran.

3.  Can I take while pregnant or breastfeeding?

You can absolutely take while pregnant or breastfeeding, and it's a great idea!

4.  Can I take it while I'm on antibiotics?

Yes, it's a good idea to take while on antibiotics, but you can't take them at the same time (or it won't do any good). You can take 4 hours away from your antibiotic dose.

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  • 5

    Posted by Jennifer on Dec 10th 2018

    Best probiotic out there!

  • 5
    Great results with MegaSpore Biotics

    Posted by Pat on Jun 20th 2018

    Saw improvement in IBS symptoms FAST!!! Also improved sleep!!!!

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